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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Contemp Clin Trials. 2011 Aug 22;32(6):953–961. doi: 10.1016/j.cct.2011.08.004

Table 4.

Comparison of randomness among PBD, MP and BUD (sample size = 300, simulation replication = 10,000)

Randomization Design Deterministic assignment probability Correct guess probability
Allocation λ PBD MP BUD PBD MP BUD
w1 = 1
w2 = 2
1 0.4443 0.4444 0.4444 0.7780 0.7779 0.7778
2 0.2891 0.1208 0.1206 0.7444 0.7080 0.7079
3 0.2126 0.0481 0.0338 0.7268 0.6840 0.6884
4 0.1706 0.0244 0.0097 0.7168 0.6741 0.6792
5 0.1412 0.0142 0.0027 0.7097 0.6676 0.6745
6 0.1163 0.0095 0.0008 0.7030 0.6632 0.6716
w1 = 2
w2 = 3
1 0.3002 0.1636 0.2999 0.7198 0.6899 0.7200
2 0.1772 0.0310 0.0312 0.6838 0.6274 0.6428
3 0.1258 0.0108 0.0032 0.6658 0.6092 0.6234
4 0.0978 0.0052 0.0003 0.6546 0.6004 0.6143
5 0.0798 0.0032 0.0000 0.6469 0.5940 0.6094
6 0.0670 0.0023 0.0000 0.6416 0.5898 0.6065
w1 = 1
w2 = 2
w3 = 2
1 0.2400 Not available 0.2399 0.6065 Not available 0.6068
2 0.1364 0.0202 0.5589 0.5120
3 0.0956 0.0017 0.5346 0.4826
4 0.0734 0.0002 0.5187 0.4674
5 0.0597 0.0000 0.5069 0.4584
6 0.0502 0.0000 0.4985 0.4520

PBD: Permuted block design

MP: Maximal procedure

BUD: Block urn design

MTI: Maximum tolerated imbalance

Correct guess uses convergent strategy