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. Author manuscript; available in PMC: 2011 Nov 2.
Published in final edited form as: Nature. 2010 Nov 11;468(7321):232–243. doi: 10.1038/nature09613

Figure 3. Arachidonic acid metabolites that may contribute to control of cerebral blood flow.

Figure 3

Arachidonic acid is formed from membrane phospholipids by Ca2+-dependent and Ca2+-independent lipases. Metabolites shown in green are vasodilators, red metabolites are vasoconstrictors, and blue denotes the location of some of the relevant enzymes. COX, cyclooxygenase; CYP, cytochrome P450 superfamily of enzymes; EET, epoxyeicosatrienoic acid; 20-HETE, 20-hydroxyeicosatetraenoic acid; HPETE, hydroperoxy-eicosatetraenoic acid.