. 2011 Sep-Oct;16(5):311–316. doi: 10.1155/2011/807123

TABLE 8.

Number of women with normal or decreased sexual desire and abnormal hormones who were treated with opioid or nonopioid analgesics

Decreased sexual desire					Normal sexual desire
Hormones	Nonmenopausal		χ²	P	Hormones	Nonmenopausal		χ²	P
Hormones	Control	Opioid	χ²	P	Hormones	Control	Opioid	χ²	P

Low FT	0/6	2/18	0.73	0.39	Low FT	0/3	2/11	0.64	0.43
Low TT	0/5	8/16	4.04	0.04	Low TT	0/3	3/11	1.04	0.31
High prolactin	0/7	1/19	0.38	0.54	High prolactin	1/3	2/11	0.32	0.57
Low DHEAS	1/7	7/19	1.22	0.27	Low DHEAS	0/3	2/11	0.64	0.43
High SHBG	0/4	2/14	0.64	0.42	High SHBG	0/3	0/6	–	–
Low T/SHBG	0/2	7/12	2.33	0.13	Low T/SHBG	0/3	2/6	1.29	0.26

Decreased sexual desire					Normal sexual desire
Hormones	Menopausal		χ²	P	Hormones	Menopausal		χ²	P
Hormones	Control	Opioid	χ²	P	Hormones	Control	Opioid	χ²	P

Low FT	0/6	2/13	1.03	0.31	Low FT	0/2	0/3	–	–
Low TT	3/6	4/13	0.65	0.42	low TT	0/2	1/3	0.83	0.36
High prolactin	0/6	1/13	0.49	0.49	High prolactin	1/2	0/3	1.88	0.17
Low DHEAS	0/6	5/13	3.13	0.08	High DHEAS	1/2	1/3	0.14	0.71
High SHBG	1/2	1/12	2.43	0.12	High SHBG	0/1	0/3	–	–
Low T/SHBG	0/2	3/12	0.64	0.43	Low T/SHBG	0/1	0/3	–	–

Data presented as n/N. DHEAS Dehydroepiandrosterone sulphate; FT Free testosterone; SHBG Sex hormone-binding globulin; T Testosterone; TT Total testosterone