Table 2.
Group differences in FA. For each cluster, the location of significant voxels, the name(s) of the major fiber tract, the position of the center of the cluster in MNI space, the size, as well as the corresponding t-value and the effect size (Cohen’s d) are listed.
| Location | White Matter Tract | X | Y | Z | Voxels mm3 |
t-value | Cohen’s d | % FA Difference |
|---|---|---|---|---|---|---|---|---|
| FH− > FH+ | ||||||||
| Dorso-medial prefrontal | R anterior scr | 20 | 13 | 40 | 43 | 3.20 | 1.17 | 13.4 |
| R anterior scr | 20 | 32 | 25 | 30 | 3.26 | 1.19 | 14.5 | |
| Dorso-lateral prefrontal | L slf | −41 | −4 | 24 | 25 | 3.23 | 1.18 | 10.8 |
| Superior/Middle Temporal | R ec/ifo | 29 | 13 | −6 | 30 | 3.32 | 1.21 | 12.3 |
| Inferior Temporal | L ilf | −56 | −37 | −6 | 29 | 3.36 | 1.14 | 24.7 |
| Subcortical | L alic | −19 | 13 | 6 | 29 | 3.14 | 1.23 | 13.1 |
| Occipital lobe | R or | 27 | −76 | 7 | 26 | 3.23 | 1.18 | 14.5 |
| FH+ > FH− | ||||||||
| Parietal lobe | L posterior scr/cs | −38 | −61 | 29 | 82 | −3.28 | 1.20 | 50.7 |
| L posterior scr/cs | −43 | −63 | 27 | 25 | −3.15 | 1.15 | 40.5 |
Abbreviations: R = right; L = left; alic = anterior limb of the internal capsule; cs = centrum semiovale; ec = extreme capsule; inferior-frontal fasciculus; ilf = inferior longitudinal fasciculus; oc = optic radiation; scr = superior corona radiata; slf = superior longitudinal fasciculus.