Table 2.
Characteristics at the initiation of hemodialysis of the 133 patients with and without cardiovascular events
| Variables | CV events (+) | CV events (-) | p value |
|---|---|---|---|
| No. of patients | 47 (35) | 86 (65) | |
| Age (y) | 66.7 ± 9.4 | 63.4 ± 10.9 | 0.10 |
| Male | 29 (62) | 48 (56) | 0.51 |
| Hypertension | 46 (98) | 79 (92) | 0.13 |
| Diabetes mellitus | 30 (64) | 46 (53) | 0.25 |
| Dyslipidemia | 38 (81) | 64 (74) | 0.40 |
| Smoking | 26 (55) | 33 (38) | 0.06 |
| Previous CV disease | 21 (45) | 31 (36) | 0.33 |
| Dose of ESA (U/week) | 9000 (4500-9000) | 9000 (9000-9000) | 0.34 |
| Statins | 16 (34) | 14 (16) | 0.02 |
| ACEI and/or ARB | 24 (51) | 41 (48) | 0.71 |
| SBP (mm Hg) | 155 ± 15 | 156 ± 23 | 0.92 |
| DBP (mm Hg) | 78 ± 10 | 80 ± 10 | 0.34 |
| Pulse pressure (mm Hg) | 76 ± 12 | 75 ± 19 | 0.51 |
| Body mass index (kg/m2) | 20 (18-23) | 21 (19-22) | 0.43 |
| Blood urea nitrogen (mg/dL) | 92 (73-114) | 90 (80-110) | 0.60 |
| Serum creatinine (mg/dL) | 8.4 (6.9-9.7) | 9.5 (8.3-10.9) | < 0.01 |
| Hemoglobin (g/dL) | 8.4 ± 1.1 | 8.1 ± 1.3 | 0.22 |
| Up/Ucr | 4.4 (2.0-7.2) | 4.6 (1.8-8.1) | 0.75 |
| Serum albumin (g/dL) | 3.1 ± 0.6 | 3.2 ± 0.6 | 0.43 |
| Ca-P product (mg2/dL2) | 51.5 (43.7-61.4) | 53.3 (43.5-65.0) | 0.58 |
| C-reactive protein (mg/dL) | 0.14 (0.05-0.44) | 0.09 (0.04-0.28) | 0.30 |
| intact-PTH (pg/mL) | 235 (150-302) | 245 (160-381) | 0.41 |
| CCA-IMT (mm) | 0.83 (0.73-0.97) | 0.77 (0.64-0.95) | 0.09 |
| CAP | 35 (74) | 51 (59) | 0.08 |
| Calcified plaque | 24 (51) | 22 (26) | < 0.01 |
| CAAC | 41 (87) | 53 (62) | < 0.01 |
| AAC | 28 (60) | 44 (51) | 0.35 |
| Low ABI | 10 (22) | 11 (13) | 0.18 |
| Duration of follow-up (months) | 19.2 (9.1-32.5) | 51.6 (38.4-65.7) | < 0.01 |
Values are expressed as the mean ± SD, number (%), or median (interquartile range). Abbreviations: CV, cardiovascular; ESA, erythropoiesis-stimulating agents; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin II receptor blockers; SBP, systolic blood pressure; DBP, diastolic blood pressure; Up/Ucr, urinary protein-creatinine ratio; Ca-P, calcium-phosphorus; PTH, parathyroid hormone; CCA-IMT, common carotid artery-intima-media thickness; CAP carotid artery plaque; CAAC, carotid artery calcification; AAC, aortic arch calcification; ABI, ankle-brachial index.