Table 3.
Risk factors for cardiovascular events by Cox analysis
| Univariate | Multivariatea | |||||
|---|---|---|---|---|---|---|
| Variable | HR | 95%CI | p value | HR | 95% CI | p value |
| Age | 1.03 | 1.00-1.06 | 0.04 | 1.01 | 0.98-1.05 | 0.38 |
| Male | 1.27 | 0.71-2.32 | 0.43 | - | - | - |
| Hypertension | 3.27 | 0.71-57.9 | 0.15 | - | - | - |
| Diabetes Mellitus | 1.49 | 0.83-2.76 | 0.19 | - | - | - |
| Dyslipidemia | 1.35 | 0.68-2.97 | 0.41 | - | - | - |
| Smoking | 1.95 | 1.09-3.52 | 0.02 | 1.73 | 0.94-3.20 | 0.08 |
| Previous CV disease | 1.40 | 0.78-2.48 | 0.26 | - | - | - |
| Pulse pressure (mm Hg) | 1.00 | 0.99-1.02 | 0.83 | - | - | - |
| Body mass index (kg/m2) | 0.98 | 0.90-1.07 | 0.69 | - | - | - |
| Up/Ucr | 1.02 | 0.97-1.07 | 0.38 | - | - | - |
| Serum albumin (g/dL) | 0.74 | 0.47-1.17 | 0.20 | - | - | - |
| Ca-P product (mg2/dL2) | 0.98 | 0.96-1.00 | 0.11 | - | - | - |
| C-reactive protein (mg/dL) | 1.19 | 0.66-1.91 | 0.53 | - | - | - |
| intact-PTH (pg/mL) | 1.00 | 0.996-1.00 | 0.14 | - | - | - |
| CCA-IMT (mm) | 2.97 | 1.20-6.52 | 0.02 | 1.51 | 0.52-3.79 | 0.43 |
| CAP | 1.69 | 0.90-3.39 | 0.10 | - | - | - |
| CAAC | 3.78 | 1.72-9.97 | < 0.01 | 2.85 | 1.18-8.00 | 0.02 |
| AAC | 1.52 | 0.85-2.77 | 0.15 | |||
| Low ABI | 1.77 | 0.83-3.43 | 0.13 | - | - | - |
Abbreviations: HR, hazard ratio; CI, confidence interval; CV, cardiovascular; Up/Ucr, urinary protein-creatinine ratio; Ca-P, calcium-phosphorus; PTH, parathyroid hormone; CCA-IMT, common carotid artery-intima-media thickness; CAP, carotid artery plaque; CAAC, carotid artery calcification; AAC, aortic arch calcification; ABI, ankle-brachial index. a The multivariate model includes variables for which p < 0.10 by univariate analysis.