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. 2011 Nov 2;6(11):e27088. doi: 10.1371/journal.pone.0027088

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Schecklmann et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A) Single pulses of paired associative stimulation conditions (PAS(45 ms), PAS(10 ms)). P1 reflects the onset of cortical processing of the auditory stimulus in secondary auditory cortex. Thus, for both PAS conditions cortical processing starts after the TMS stimulus with the PAS(45 ms) being more close to the P1 than the PAS(10 ms). Therefore both conditions are considered inhibitory with a more pronounced inhibition for the PAS(45 ms). B) Study design (AEPs = acoustic evoked potentials; TMS = transcranial magnetic stimulation; PAS = paired associative stimulation). C) Protocol of the measurement of auditory evoked potentials.