Figure 12. CeUGGT-2 plays a role in alleviating endogenous ER stress during development.
F2 Control gfp(RNAi), uggt-1(RNAi) and uggt-2(RNAi) worms of ire-1 (A), atf-6 (B) and pek-1 (C) strains were tested under 0 and 2.5 µg/ml TN concentrations. Gravid hermaphrodites were allowed to lay eggs for 6 h and the developmental stages were analyzed for 5 days at intervals of 24 h. The percentages of L1, L2/L3, L4 and adults were determined. Studies were performed for three independent cohorts (n>100) and the values are the mean of the three experiments.
