Figure 5. Amino acid residues potentially under positive selection in the C3 region of Env gp120.

The dN/dS ratio was estimated for each amino acid residue in the C3 region of gp120 among 10 amino acid sequences derived from an individual, as described in Methods. The data obtained from 15 patient samples were then plotted together. Amino acid numbering is based on the HXB2 Env gp120.