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. 2011 Nov 2;6(11):e27259. doi: 10.1371/journal.pone.0027259

Figure 4. Effect of p38 inhibition on cytoskeletal organization and MRTF-A localization.

Figure 4

(A) Representative images of paxillin (green) and F-actin (red) localization in keratinocytes treated with carrier or 2 µM SB202190 for 24 h. Scale bar  = 20 µm (B) Representative image of MRTF-A localization in keratinocytes transfected with FLAG-MRTF-A construct, treated overnight with or without SB202190 and then stimulated with 1 µM cytochalasin D for 1 h. MRTF-A was detected by immunofluorescence staining for the FLAG tag. N = 20 cells examined per condition. Scale bar  = 50 µm.