Figure 4.

Predicted and observed F_st. (A) The predicted and observed F_st values between an admixed Mestizo population and a European founding population are plotted against the European admixture fraction γ in the Mestizo population, estimated by maximum likelihood. The prediction is based on eq. 7, using the European and Native American allele frequencies estimated from Wang et al. (2008) as $\underset{¯}{p_1}\text{ and }\underset{¯}{p_2}$, respectively, together with the maximum likelihood estimate of γ. The observation is based on F_st estimated from eq. 1, inserting estimated allele frequencies from Wang et al. (2008) on European and Mestizo populations. (B) The observed F_st value is plotted against the predicted F_st value. The identity line is shown in gray. In both panels, each point represents one of the 678 loci used. The correlation coefficient between the predicted and observed F_st values is 0.978.