Table 1.
Characteristics of Cases and Controls in Relation to History of Hormone Therapy Use, Seattle, Washington, 1985–2005
| Never users of any hormone therapy | Users of continuous-combined EPTa | |||
|---|---|---|---|---|
| Cases (N=774) N (%) |
Controls (N=1116) N (%) |
Cases (N=90) N (%) |
Controls (N=227) N (%) |
|
| Age (years) | ||||
| 45–49 | 60 (8) | 115 (10) | 0 (0) | 2 (1) |
| 50–54 | 187 (24) | 290 (26) | 20 (22) | 57 (25) |
| 55–59 | 175 (23) | 236 (21) | 33 (37) | 65 (29) |
| 60–64 | 161 (21) | 215 (20) | 22 (24) | 60 (26) |
| 65–69 | 147 (19) | 179 (16) | 11 (12) | 36 (16) |
| 70–74 | 44 (6) | 81 (7) | 4 (4) | 7 (3) |
| Education | ||||
| < High school | 70 (9) | 110 (10) | 5 (6) | 14 (6) |
| High school graduate | 246 (31) | 315 (28) | 16 (18) | 55 (24) |
| Some college | 245 (32) | 355 (32) | 25 (28) | 63 (28) |
| College graduate | 213 (28) | 366 (30) | 44 (49) | 95 (42) |
| Body mass index (kg/m2) | ||||
| < 25.0 | 193 (25) | 600 (54) | 41 (46) | 136 (60) |
| 25.0 – 29.9 | 195 (25) | 290 (26) | 28 (31) | 58 (26) |
| ≥ 30.0 | 381 (50) | 221 (20) | 21 (23) | 33 (15) |
| Unknown | 5 | 5 | 0 | 0 |
| Age at menarche (years) | ||||
| ≤ 11 | 204 (26) | 244 (22) | 18 (20) | 50 (22) |
| 12 | 212 (27) | 278 (25) | 20 (22) | 52 (23) |
| ≥ 13 | 358 (46) | 593 (53) | 52 (58) | 125 (55) |
| Unknown | 0 | 1 | 0 | 0 |
| Oral contraceptive use | ||||
| Never use | 450 (59) | 629 (57) | 34 (38) | 67 (30) |
| Ever use: | ||||
| 6 months – 5 years | 203 (26) | 250 (23) | 35 (39) | 78 (35) |
| > 5 years | 114 (15) | 231 (21) | 20 (22) | 81 (36) |
| Unknown | 7 | 6 | 1 | 1 |
| Parity | ||||
| Nulliparous | 145 (19) | 146 (13) | 19 (21) | 26 (11) |
| 1 | 92 (12) | 128 (11) | 14 (16) | 20 (9) |
| 2 | 217 (28) | 325 (29) | 30 (33) | 79 (35) |
| ≥ 3 | 319 (41) | 517 (46) | 27 (30) | 102 (45) |
| Unknown | 1 | 0 | 1 | 0 |
| Age at first birth (years) | ||||
| Nulliparous | 145 (19) | 146 (13) | 19 (21) | 26 (11) |
| < 20 | 148 (19) | 156 (14) | 13 (14) | 36 (16) |
| 20 – 24 | 306 (40) | 445 (40) | 32 (36) | 89 (39) |
| ≥ 25 | 174 (23) | 369 (33) | 26 (29) | 76 (33) |
| Unknown | 1 | 0 | 0 | 0 |
| Cigarette smoking status | ||||
| Never smoker | 448 (58) | 534 (48) | 57 (63) | 116 (51) |
| Former smoker | 234 (30) | 359 (32) | 23 (26) | 73 (32) |
| Current/recent smoker | 92 (12) | 223 (20) | 10 (11) | 38 (17) |
a
EPT = estrogen-progestin therapy