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. 2011 Nov 15;359(2):163–175. doi: 10.1016/j.ydbio.2011.08.015

Fig. 1.

Fig. 1

A. Anterior foregut region at E9.5. The thyroid and lung primordia can be distinguished as discrete regions of the ventral endoderm expressing Nkx2-1, located in close vicinity of the developing heart. B. At E10.5 the thyroid primordium forms a caudally directed bud that is closely apposed to the aortic sac. C. The lung buds at E10.5 form hollow, blind-ended epithelial tubes surrounded by concentric layers of mesenchyme. Sagittal sections. As, aortic sac; h, heart; lu, lung primordium; th, thyroid primordium; ve, ventral endoderm. Scale bars = 100 μm in A, 75 μm in B and C.