Table 1.
Correlation between changes in mRNA expression and protein abundance in the lactating mammary gland relative to the non-lactating phenotype.
| Transporter | mRNA | Protein | Correlation | Predicted Regulation |
|---|---|---|---|---|
| Exporters | ||||
| ZnT1 | No change | Decreased | No | Degradation |
| ZnT2 | Increased | Increased | Yes | Transcription |
| ZnT4 | Increased | Increased | Yes | Transcription |
| ZnT5 | No change | No change | Yes | Transcription |
| ZnT6 | No change | Decreased | No | Degradation |
| ZnT7 | Increased | Not Detected | No | Degradation |
| ZnT8 | Increased | Decreased | No | Degradation |
| ZnT9 | No change | Increased | No | Stabilized |
| ZnT10 | No change | Decreased | No | Degradation |
| Importers | ||||
| Zip1 | No change | No change | Yes | Transcription |
| Zip3 | Increased | Increased | Yes | Transcription |
| Zip4 | No change | Decreased | No | Degradation |
| Zip5 | No change | Increased | No | Stabilized |
| Zip6 | Increased | Not Detected | No | Degraded |
| Zip7 | No change | Increased | No | Stabilized |
| Zip8 | Increased | Increased | Yes | Transcription |
| Zip9 | Increased | Not Detected | No | Degradation |
| Zip10 | Increased | Increased | Yes | Transcription |
| Zip11 | Increased | Increased | Yes | Transcription |
| Zip12 | No change | Decreased | No | Degradation |
| Zip13 | No change | No change | Yes | Transcription |
| Zip14 | Increased | No change | No | Post-transcription |