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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Jun 25;1820(3):417–426. doi: 10.1016/j.bbagen.2011.06.019

Figure 9.

Figure 9

Schematic representation of the energy landscape for a single lobe of Tf at neutral pH showing the existence of two alternative conformations (open and closed) and the influence of metal binding on their relative Boltzmann weights.