Figure 1. Experimental Design of the Context Pre-Exposure Rescue of the Immediate Shock Deficit Assay.
Saline or ethanol is administered to both the non-pre-exposed and pre-exposed groups on Day 1. To control for handling, the non-pre-exposed groups are placed in a distinctly different context in a different room, while the pre-exposed groups are placed in the conditioning context. On Day 2, both groups undergo immediate shock training in the conditioning context. Day 3 consists of an 8 minute context test in the conditioning context.