Table 1.
Demographic, Clinical and Positron Emission Tomography Procedural Characteristics
| PTSD (n=15) | Healthy Control (n=15) | P Value | |
|---|---|---|---|
| Age (yrs) | 32.9 9.8 | 30.1 10.0 | 0.45 |
| Range | 21 – 51 | 18 – 49 | - |
| Sex (M, F) | 9M, 6F | 10M, 5F | 0.71 |
| Ethnicity | 4C, 5AA, 5H | 10C, 4AA | - |
| BMI | 29.7 5.2 | 26.5 4.6 | 0.09 |
| Smoking status (Y/N) | 2/15 | 1/15 | 0.54 |
| Index Trauma Type(Combat/Non-Combata) | 5/10 | - | - |
| No. Lifetime Criteria A Traumas | 5.4 ± 3.0 | - | |
| CAPS Total Score | 68.4 15.8 | - | - |
| CAPS Re-Experiencing Sub-Score | 18.8 5.6 | - | - |
| CAPS Avoidance Sub- Score | 27.5 8.1 | - | - |
| CAPS Hyperarousal Sub- Score | 22.1 6.2 | - | - |
| HAM-A Total Score | 18.5 6.9 | 2.5 5.1 | <0.001 |
| MADRS Total Score | 26.5 8.6 | 4.2 4.4 | <0.001 |
| Injected Dose (MBQ) | 710 38 | 699 53 | 0.53 |
| Specific Activity(MBQ/nmol) | 203 144 | 219 124 | 0.75 |
| Injected Mass (μg) | 1.57 1.04 | 1.34 0.85 | 0.52 |
Data presented in mean ± standard deviation, unless otherwise indicated. P values determined by independent sample t-tests for continuous variables or by chi-square for dichotomous variables.
AA, African-American; AS, Asian-American; BMI, body mass index; C, Caucasian; F, female; H, Hispanic; HAMA-A, Hamilton Anxiety Scale; M, male; MARDS, Montgomery-Asberg Depression Rating Scale; PTSD, posttraumatic stress disorder; N, nonsmoker; S, smoker.
a
Non-combat trauma exposure consisted of physical or sexual assault, domestic violence or natural disaster.