Table 3.
Adjusted hazard ratios (95% CI) for the final model for lung cancer for males and females in the derivation cohort
| Adjusted hazard ratios for females (95% CI) | Adjusted hazard ratios for males (95% CI) | |
|---|---|---|
| Symptoms presented to GP | ||
| Current haemoptysisa | 23.9 (20.6 to 27.6) | 21.5 (19.3 to 23.9) |
| Current appetite lossa | 4.14 (3.15 to 5.45) | 4.71 (3.69 to 6.00) |
| Current weight lossa | 4.52 (3.80 to 5.38) | 6.09 (5.33 to 6.95) |
| New onset cough in last 12 monthsa | 1.90 (1.56 to 2.32) | 1.47 (1.23 to 1.75) |
| Recorded haemoglobin<11 g/dl in last 12 monthsa | 1.75 (1.38 to 2.22) | 1.89 (1.54 to 2.32) |
| Smoking status | ||
| Non smoker | 1 | 1 |
| Ex-smoker | 3.37 (2.83 to 4.01) | 2.13 (1.87 to 2.43) |
| Light smoker (<10/day) | 6.57 (5.37 to 8.03) | 3.70 (3.20 to 4.27) |
| Moderate smoker (10-19/day) | 8.32 (7.05 to 9.82) | 4.95 (4.26 to 5.76) |
| Heavy smoker (≥20/day) | 10.6 (8.49 to 13.2) | 6.35 (5.43 to 7.43) |
| Prior diagnosis other cancer except lung cancera | 1.33 (1.09 to 1.63) | NS |
| Chronic obstructive airways diseasea | 1.82(1.57 to 2.11) | 1.51 (1.34 to 1.69) |
| Townsend deprivation score (5 unit increase) | 1.17(1.08 to 1.27) | 1.17 (1.10 to 1.24) |
a
Compared with person without this characteristic. NS = not significant. Hazard ratios were adjusted for all other terms in the table and models accounted for age as underlying time function and also included fractional polynomial terms for body mass index (BMI). For females, the terms were BMI-2, ln(BMI). Formales the terms were BMI-1, BMI-1 ln(BMI).