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. Author manuscript; available in PMC: 2012 Oct 19.
Published in final edited form as: Bioconjug Chem. 2011 Sep 30;22(10):2136–2142. doi: 10.1021/bc200411n

Figure 4.

Figure 4

Spatial activation of gene expression using a PhotoPEGylated antisense agent. NIH 3T3 cells were transfected with pEGFP-N1, pDsRed-Monomer, and AA-20K PhotoPEG. Only one half side of the well was irradiated for 2 min (25 W, 365 nm) and the cells were imaged after 48 h. The DsRed channel is shown above the EGFP channel. AA: non-modified antisense agent. AA-HP: hairpin antisense agent. AA-20K PhotoPEG: 20 kDa photocleavable antisense agent.