Table 1.
Distance between α-carbons for homologous positions in the M3 segment and M3–S2 linker in the A/C and B/D subunits in GluA2cryst
| GluA2 | Distance between αCs (Å) |
GluN1 | GluN2A | GluN2C | |
|---|---|---|---|---|---|
| A/C | B/D | ||||
| P632 | 26.6 | 49.6 | R | Q | T |
| S631 | 19.7 | 42.7 | E | D | D |
| V630 | 18.2 | 35.8 | E | V | I |
| M629 | 12.0 | 30.2 | P | F | Y |
| R628 | 16.9 | 22.7 | R | E | Q |
| E627 | 19.1 | 19.6 | D | E | E |
| V626 | 12.7 | 12.2 | L | Q | Q |
| T625 | 11.3 | 10.2 | V | I | I |
| L624 | 14.9 | 15.9 | L | M | M |
| F623 | 17.0 | 17.2 | F | F | F |
| A622 | 10.4 | 10.8 | A | A | A |
Shown are residues in GluA2cryst (Sobolevsky et al., 2009) (PDB ID 3KG2) and homologous positions in GluN1, GluN2A, or GluN2C. Underlined residues for GluA2cryst are part of the M3 helix for the A/C and B/D subunits. Bold residues are the additional helical component of the A/C subunit. Average distances for positions shown are 16.3 Å (A/C) and 24.3 Å (B/D).