TABLE 2.

Listed are both the initial values of the parameters and the bounds that defined the search space used in the genetic algorithm to improve congruency between ABM and CMM predictions of smooth muscle and collagen mass via Eq. (5). Note that 16 parameters were allowed to vary: CMM (top 4 rows) and ABM (bottom 12 rows). See Eqs. (1) and (2), the Appendix, and Table 1 in Thorne et al.¹⁵ for associated constitutive equations, definitions, or rules. Also listed are the final values of the parameters following minimization.

Parameter	Initial Value	Lower Bound	Upper Bound	After Genetic Algorithm
$K_{{\sigma }_{\theta }}^c$	1	0.1	10	1.11
$K_{{\sigma }_{\theta }}^m$	10	0.1	10	3.85
$K_{{\tau }_w}^c$	1	0.1	10	2.85
$K_{{\tau }_w}^m$	10	0.1	10	8.75
MMP-10	2.69E-04	2.69E-05	2.69E-03	9.47E-04
MMP-1%A	0.39	0.039	3.93	1.04
C0	0.009	0.0009	0.09	0.07
CTGF	114.94	11.49	1149.42	134.57
Mp	−1.45E+09	−1.45E+10	−9.69E+08	−1.53E+09
M0	80000	53333.33	120000	6.12E+04
Ma1	71020	7102	106530	9.89E+04
Ma2	100	66.66	1000	223.21
PDGFσθ	4.79E-07	3.19E-07	7.19E-07	7.03E-07
PDGF0	4.17E-05	4.17E-06	6.25E-05	6.17E-05
TGFβσθ	1.65E-06	1.65E-07	1.65E+05	7.87E-06
TGFβ0	1.03E-04	1.03E-05	1.03E-03	3.69E-04