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. 2011 Oct 28;2(11):3223–3231. doi: 10.1364/BOE.2.003223

Fig. 1.

Fig. 1

(a) One UV photon is absorbed by the antibody and the disulfide bridge is opened thereby forming thiol groups. Their interaction with the gold surface leads to oriented Fab region so that the upside down position (circled in the right side of the picture) is hampered and the antigen binding is more effective.