FIGURE 3.

LCN13 Tg mice resist diet-induced hepatic steatosis. Tg and WT male littermates (7 weeks old) were fed a high fat diet. Mice were fasted for 16 h and killed. A, plasma TAG levels at 18 weeks of age. B, liver weights at 20 weeks of age. C, liver TAG levels at 20 weeks of age (normalized to liver weights). D, gene expression measured by qRT-PCR and normalized to 36B4 expression. Error bars represent S.E. *, p < 0.05. a.u., arbitrary units; MCAD, medium-chain acyl-CoA dehydrogenase; LCAD, long-chain acyl-CoA dehydrogenase.