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Hsp70 binds to (Hsp90)2 and Hop to form an intermediate complex. (A) MS of an intermediate complex (Hsp90)2(Hop)1(Hsp70)1 (pink) formed after addition of Hsp70 following Hop binding to the (Hsp90)2. B) Addition of FKBP52 to the intermediate complex to form (Hsp90)2(Hop)1(FKBP52)1(Hsp70)1 (olive green), (SI Appendix, Figs. S6 and S7 for additional quaternary complexes).
