Fig. 4.

ABIN1-deficient bone marrow-derived cells promote inflammation. (A and B) Lethally irradiated WT mice were reconstituted with fetal liver cells of the indicated genotypes and analyzed 12 wk later for blood neutrophil counts and hemoglobin (Hb) concentration (A) and total splenic numbers of CD11b⁺ cells (B) (n = 5). (C) Chimeric mice were killed 12 wk post transplantation, and H&E-stained tissue sections of lung (a and b), liver (c and d), and kidney (e and f) were analyzed by microscopy. (Scale bar: 80 μM.)