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Fates of sister chromatids of a single chromosome during mitosis. Corresponding daughter HCT116 cells expressing lacIGFP with LacO arrays integrated into a single chromosome were fixed and imaged after inducing high levels of merotely with MCAK siRNA or monastrol washout. Schematic of possible segregation fates of the marked chromosome (Upper) and representative images of each fate (Lower) are shown. (Scale bar: 10 μm.)
