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. 2011 Oct 24;108(44):18144–18149. doi: 10.1073/pnas.1108416108

Fig. 3.

Fig. 3.

Mania-like behavior in Myk/+ mice. (A) Myk/+ prefer to explore the open arm of the EPM (+/+ mice n = 29, Myk/+ n = 19) and (B) the light side of the LDB (+/+ mice n = 27, Myk/+ n = 18) for longer durations than +/+ mice. (C) Myk/+ (n = 8) show a higher preference for 0.1% sucrose than +/+ mice (n = 16) over 4 d and (D) consume more sucrose on the first presentation of sucrose. W, water; S, sucrose. (E) Myk/+ (n = 14) are active for a longer duration than +/+ mice (n = 15) in the Porsolt forced swim test. (F) PPI scores are impaired in Myk/+ (n = 20) compared with +/+ mice (n = 33) at all prepulse intensities tested. (G and H) Myk/+ (n = 16) had a startle habituation deficit compared with +/+ when presented with a repeated auditory stimulus (n = 12). All data are presented as means ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001 compared with +/+ mice.