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(A) Representative electron microscopic images of midperipheral RPE from control and mutant animals. Neural retina was removed in these samples to facilitate imaging of RPE microvilli. Note the presence of a large cytoplasmic inclusion in the 174delG image (arrow). Scale bar, 2 μm. (B) The average microvillus densities of three biological replicates per group are displayed (P = 0.001, ANOVA).
