Table 1. Effect of various MGO concentrations on contents of total cholesterol, LDL-cholesterol and triglycerides in the plasma of naïve rats (without induction of hyperlipidemia).

		Rat group
MGO dose	Plasma lipid content	Placebo	+MGO	Lipid content decrease
				after MGO treatment (%)
2.5%	Total cholesterol	57.3±4.4	40.7±4.2 (<0.0001)	29.0
2.5%	LDL cholesterol	18.5±1.6	14.0±1.0 (0.0002)	23.9
2.5%	Triglycerides	85.5±15.0	67.5±15.7 (0.07)	21.1
4%	Total cholesterol	69.3±8.5	32.1±6.6 (<0.0001)	53.6
4%	LDL cholesterol	13.2±2.2	7.3±1.4 (<0.0003)	45.2
4%	Triglycerides	114.8±14.4	79.6±14.20 (0017)	30.6

The placebo (control) group was administered 1 ml carrier alone. The MGO treated group received a dose of MGO cocktail. The injected cocktails of different doses of MGO consisted of: 2.5% or 4% MGO (v/v) in 1 ml carrier. Twenty-four h later, blood was collected from the hearts of animals in heparinized tubes and plasma samples were prepared and assayed for total cholesterol, LDL-cholesterol, and triglycerides. The values represent mean ± SD of six rats. p-values of unpaired Student's t test (two-tailed) are shown in parentheses (MGO-treated rat groups vs placebo-receiving group).