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. 2011 Nov 3;6(11):e20516. doi: 10.1371/journal.pone.0020516

Table 4. The anti-hyperlipidemic action of MGO is associated with camphene.

Rat Group Percent change
Plasma lipid (A) (B) (C) (D) +Mixture
content (mg/dl) Placebo Triton WR-1339 +Mixture A +Mixture B A B
+Triton WR-1339 +Triton WR-1339
Total cholesterol 65.1±6.9 262.9±32.3 263.4±23.7ns 156.7±12.3*** +1.2 −40.4
LDL-cholesterol 16.4±2.8 47.6±9.1 45.4±10.7ns 18.5±2.7*** −4.7 −61.1
Triglycerides 130.2±22.6 1950.8±191.1 1976±140.7ns 888.7±99.3*** +1.3 −54.4

The placebo group (A) was administered 1 ml carrier alone. The Triton WR-1339 group (B) was administered 1 ml carrier and one h later 1 ml of Triton WR-1339 (200 mg/kg). Animals in (C) and (D) received Mixture A and Mixture B, respectively, in 1 ml carrier and one hour later received Triton WR-1339. Mixture A consisted of α-pinene, β-pinene, myrcene, β-caryophyllene and linalool; and Mixture B consisted of Mixture A+camphene. The constituents in Mixtures A and B were present at concentrations identical to those contained in the 4% MGO dose. The percent change caused by Mixture A and B treatments is expressed relative to measurement in the group of Triton WR-1339-treated rats (B), which was defined as 100%. The values represent mean ± SD of six rats. Significantly different values were obtained in Mixture B-treated rats compared to Triton WR-1339-treated rats with p<0.001 (***) by the Student-Newmann-Keuls test. Values of Mixture A-treated rats vs Triton WR-1339-treated rats were non significant, ns (p>0.05).