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. 2011 Nov 3;6(11):e27287. doi: 10.1371/journal.pone.0027287

Figure 6. Histochemical analysis of NPC2 replacement therapy in murine spleen sections.

Figure 6

Hematoxylin-eosin (H&E) staining of spleen from saline treated wild type mice (left panel), saline treated NPC2−/− mice (middle panel), and NPC2 treated NPC2−/− mice (right panel). Massive accumulation of lipid droplets was most prominent observed in the spleens of saline treated NPC2−/− mice. Data are representative of three separate experiments. n = 3 animals in each experimental group. Scale bares represent 100 µm.