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Total cholesterol levels in cerebellum, cortex, and hippocampus was measured postmortem in saline treated wild type mice (black bars), saline treated NPC2−/− mice (light gray bars), and NPC2 treated NPC2−/− mice (dark gray). Each bar represents the mean ± SEM for 6 animals in each of the three groups. Bars not sharing a letter within a given panel are significantly different (P<0.05).
