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. 2011 Oct 17;30(1):98. doi: 10.1186/1756-9966-30-98

Figure 4.

Figure 4

Effects of DNMT1 silencing on gene methylation and mRNA expression of seven tumor suppressor genes in Hela cells assayed by MeDIP combined with Real-Time PCR. Except for FHIT and PTEN, the rest five suppressor genes CCNA1, CHFR, PAX1, SFRP4 and TSLC1 in transfected group displayed lower level of methylation with increased mRNA expression when compared with control group. (n = 3, **P < 0.01).