Table 2.
Study | No. Patients | Regimen | EFS/DFS/FFS (%) | OS (%) |
---|---|---|---|---|
Sirohi et al.9 | 195 | MBE/ME | 5-y: 44; 10-y: 37 | 5-y: 55; 10-y: 49 |
PR: 44; NR: 14 | PR: 59; NR: 17 | |||
Stiff et al.43 | 81 | E, Cy, TBI | 5-y: 41 | 5-y: 54 |
Sureda et al.8 | 357 | Various | 5-y: 49 | 5-y: 57 |
Tarella et al.44 | 102 | Mitx/Must | 5-y: 53; CR: 78 | 5-y: 64; CR: 88 |
PR: 41; NR: 7 | PR: 58; NR: 13 | |||
Wadehra et al.45 | 127 | BuCyE | 5-y: 48 | 5-y: 51 |
Czyz et al.46 | 341 | Various | 5-y: 45; CS: 62 | 5-y: 64; CS: 79 |
Res: 46 | CR: 77; PR: 71; | |||
< PR: 33 | ||||
Engelhardt et al.47 | 115 | Various | 5-y: 46 | 5-y: 58 |
Lavoie et al.48 | 100 | Various | 15-y: 54 | |
First relapse: 67 | ||||
Primref: 39 | ||||
Adv: 29 |
Abbreviations: Adv, advanced disease; B, carmustine; Bu, busulfan; CR, complete remission; CS, chemosensitive; Cy, cyclophosphamide; DFS, disease-free survival; E, etoposide; EFS, event-free survival; FFS, failure-free survival; M, melphalan; Mitx, mitoxantrone; Must, mustard; NR, no response; OS, overall survival; PR, partial remission; Primref, primary refractory; Res, resistant disease; TBI, total body irradiation.