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NOX2 deletion reduces glial activation during I/R injury. (A) Western blot analysis shows increases in GFAP at 5 days after ischemic injury that was reduced by NOX2 deletion. (B) Fluorescent microscopic imaging of retinal sections labeled with GFAP. Scale bar, 50 μm. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer.
