Table 5.

The rate of decrease in ulcer size (ulcers at least 400 mm²)

	Week 4	Week 8
mean ± SD (95% CI)
2-sample t test (ns)
H2RA	89.3 ± 10.7%	99.7 ± 1.0%
(n = 17)	(84.2–94.4)	(99.2–100)
PPI	85.6 ± 25.2%	99.5 ± 1.4%
(n = 20)	(74.5–96.6)	(98.9–100)

The mean size of 17 ulcers exceeding 400 mm² was 804.8 ± 496.8 mm² in the H₂RA group and the rate of decrease in size was 89.3 ± 10.7% at Week 4 and 99.7 ± 1.0% at Week 8. The mean size of 20 large ulcers was 896.5 ± 533.4 mm² in the PPI group and the rate of decrease in size was 85.6 ± 25.2% at Week 4 and 99.5 ± 1.4% at Week 8. There were no significant differences between the two groups. H₂RA, H₂ receptor antagonist; PPI, proton pump inhibitor.