Table 2.
Weight loss (crude and imputed if missing), body mass index reduction, and physical activity change at programme end and one year follow-up. Values are means (95% CI)
| Weight Watchers | Slimming World | Rosemary Conley | Size Down | General practice | Pharmacy | Choice | Exercise/comparator | |
|---|---|---|---|---|---|---|---|---|
| Weight loss at programme end (kg) | ||||||||
| BOCF† | 4.43 (3.6 to 5.3)** | 3.56 (2.7 to 4.4)** | 4.23 (3.2 to 5.2)** | 2.38 (1.7 to 3.1)** | 1.37 (0.4 to 2.3)* | 2.11 (1.0 to 3.2)** | 3.32 (2.5 to 4.1)** | 2.01 (1.2 to 2.8)** |
| Complete cases only‡ | 5.15 (4.2 to 6.1)** | 4.25 (3.3 to 5.2)** | 5.29 (4.2 to 6.4)** | 3.22 (2.3 to 4.1)** | 2.17 (0.7 to 3.7)* | 2.80 (1.4 to 4.2)** | 3.81 (2.9 to 4.7) | 2.96 (1.8 to 4.1)** |
| LOCF‡ | 4.71 (3.9 to 5.6)** | 3.76 (2.9 to 4.6)** | 4.37 (3.4 to 5.4)** | 2.37 (1.7 to 3.1)** | 1.13 (0.0 to 2.3) | 2.14(1.0 to 3.2,)** | 3.56 (2.8 to 4.3)** | 1.87 (1.0 to 2.78)** |
| Physical activity change to programme end (kcal/week) | ||||||||
| BOCF† | 1926 (1225 to 2629)** | 1899 (1226 to 2571)** | 1801 (1155 to 2447)** | 1480 (701 to 2259)** | 1895 (963 to 2826)** | 2720 (1790 to 3649)** | 1986 (1245 to 2727)** | 1608, (988 to 2228)** |
| Complete cases only‡ | 1946 (1238 to 2654)** | 1957 (1267 to 2648)** | 1856 (1193 to 2520)** | 1542 (733 to 2351)** | 1980 (1010 to 2949)** | 2885 (1912 to 3857)** | 2159 (1362 to 2955)** | 1747 (1080 to 2415)** |
| Change in physical activity to programme end (minutes/week)§ | ||||||||
| Moderate and vigorous | 58 (42 to 75) | 60 (42 to 79) | 49 (33 to 65) | 55 (35 to 75) | 47 (25 to 70) | 73 (51 to 94) | 59 (40 to 77) | 51 (36 to 67) |
| Walking | 7 (−6 to 19) | 1 (−12 to 13) | 14 (2 to 26) | 16 (3 to 29) | 12 (−4 to 28) | 1 (−11 to 14) | 5 (−6 to 17) | 7 (−3 to 18) |
| Weight loss at one year | ||||||||
| BOCF† | 3.46 (2.1 to 4.8)** | 1.89 (0.9 to 2.9)** | 2.12 (0.9 to 3.4)** | 2.45 (1.3 to 3.6)** | 0.83 (−0.4 to 2.0) | 0.66 (−0.4 to 1.7) | 2.15 (0.9 to 3.4)** | 1.08 (0.1 to 2.1)* |
| Complete cases only‡ | 4.43 (2.7 to 6.1)** | 3.10 (1.5 to 4.7)** | 3.27 (1.4 to 5.1)** | 3.71 (2.0 to 5.4)** | 1.26 (−0.6 to 3.1) | 1.19 (−0.7 to 3.1) | 2.94 (1.2 to 4.7)** | 1.66 (0.1 to 3.2)* |
| LOCF‡ | 4.35 (3.0 to 5.7)** | 3.28 (2.2 to 4.4)** | 3.17 (1.8 to 4.5)** | 3.10 (1.9 to 4.3)** | 1.13 (−0.1 to 2.4) | 1.85 (0.5 to 3.2)* | 2.96 (1.7 to 4.3)** | 1.33 (0.2 to 2.4)* |
| Physical activity change to one year (kcal/week) | ||||||||
| BOCF† | 2048 (1262 to 2834)** | 1362 (645 to 2078)** | 1429 (657 to 2202)** | 1429 (644 to 2213)** | 861 (256 to 1467)* | 1473 (742 to 2203)** | 1642 (837 to 2448)** | 1766 (1044 to 2487)** |
| Complete cases only‡ | 2069 (1276 to 2861)** | 1404 (666 to 2141)** | 1473 (678 to 2268)** | 1488 (673 to 2303)** | 861 (256 to 1467)* | 1562 (792 to 2332)** | 1659 (846 to 2472)** | 1899 (1129 to 2668)** |
| Change in physical activity to one year (minutes/week)§ | ||||||||
| Moderate and vigorous | 60 (40 to 79) | 21 (3 to 39) | 25 (10 to 40) | 19 (4 to 33) | 14 (−6 to 35) | 27 (3 to 51) | 32 (14 to 50) | 42 (25 to 60) |
| Walking | −2 (−15 to 12) | −9 (−22 to 4) | −3 (−8 to 13) | 7 (−7 to 21) | −12 (−26 to 3) | 17 (−0.4 to 34) | −2 (−14 to 9) | −3 (−14 to 8) |
| Body mass index reduction at one year (kg/m2) | ||||||||
| BOCF† | 1.17 (0.7 to 1.7)** | 0.71 (0.4 to 1.0)** | 0.75 (0.3 to 1.1)** | 0.67 (0.3 to 1.0)** | 0.32 (−0.1 to 0.7) | 0.31 (0.0 to 0.7) | 0.90 (0.5 to 1.3)** | 0.45 (0.1 to 0.8)* |
| Complete cases only‡ | 1.8 (1.1 to 2.5)** | 1.36 (0.7 to 2.0)** | 1.33 (−0.6 to 2.0)** | 1.19 (0.5 to 1.8)** | 0.66 (−0.1 to 1.4) | 0.73 (−0.1 to 1.6) | 1.42 (0.8 to 2.1)** | 0.79 (0.2 to 1.4)* |
BOCF=baseline observation carried forward; LOCF=last observation carried forward.
*P<0.05 (paired t test from baseline).
**P≤0.001 (paired t test from baseline).
†Primary analysis.
‡Sensitivity analyses.
§Change from baseline in minutes/week using baseline observation carried forward.