Table 3.
Summary of demographic and clinically important matching criteria used by Price et al. [77] and Barnes et al. [78] to ensure baseline similarity of patients in the different treatment arms
Matching criterion | Categories |
---|---|
Oral corticosteroid prescriptions during baseline year | 0, 1, 2, 3, ≥4 |
Sex | Male/female |
Mean SABA dose during the baseline year, μg/d | 0 |
1–100 | |
101–200 | |
201–300 | |
301–400 | |
≥400 | |
Age | ≥13 ± 5 y or |
6–12 ± 3 y or | |
5 ± 1 y | |
For step-up population only: mean ICS dose prescribed during the baseline year, μg/d | 0–99 |
100–199 | |
200–299 | |
300–399 | |
400–599 | |
600–799 | |
≥800 | |
For EF HFA-BDP vs CFC-BDP analysis only: number of asthma consultations without resulting in a prescription for oral corticosteroids | 0, 1, 2, 3 |
CFC-BDP chlorofluorocarbon beclomethasone dipropionate, EF HFA-BDP extra-fine hydrofluoroalkane beclomethasone dipropionate, ICS inhaled corticosteroid, SABA short-acting β2-agonist