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(A) Summary data of diameter changes (as % of passive diameter) of rat middle cerebral arteries (n=6) as a function of intraluminal pressure (mm Hg) and pressure+flow (Δmm Hg). (B) Changes of estimated CBF (eCBF) in arbitrary units (unit) as a function of pressure (mm Hg) and pressure+flow (Δmm Hg). Calculated gain (G) of CBF was 0.8±0.01 when pressure was raised, and increased to 0.99±0.01 when pressure+flow were raised. Data are mean±s.e.m. (*P<0.05).
