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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Health Phys. 2011 Dec;101(6):731–738. doi: 10.1097/HP.0b013e3182166759

Table 1.

Rhabdomyocyte survival at 48 hours. 48hr mean percent survival (±SEM) of non-IR exposed cells, as well as survival of IR-exposed cells receiving P188 alone, PEG alone, cofactor NAC alone as well as combined with P188 or MgATP and P188 with NAC and MgATP.

Treatment Baseline Sham-exposed 48hrs Post-Radiation (40Gy)
0hr Control 48hr Control No Treatment Treatment
1mM P188 89.9% ± 1.5 83.3% ± 2.2 4.8% ± 0.6 8.1% ± 1.5a
1mM PEG 89.9% ± 1.5 87.3% ± 3.1 6.8% ± 1.0 7.1% ± 1.4
10mM NAC 89.9% ± 1.5 85.3% ± 3.1 6.8% ± 1.0 13.4% ± 3.8a
1mM P188, 10mM NAC 86.9% ± 2.1 88.0% ± 1.1 7.8% ± 1.9 31.2% ± 1.1a
10mM NAC, 0.1mM MgATP 86.9% ± 2.1 82.5% ± 1.2 5.5% ± 1.6 19.9% ± 1.7a
1mM P188, 10mM NAC, 0.1mM MgATP 86.9% ± 2.1 81.7% ± 1.0 7.2% ± 1.4 29.5% ± 3.0a
a

Results are significantly different than irradiated, untreated samples