Table 4.
Frequencies of the WDR36 Inferred Diplotypes in Cases and Controls
| Diplotype | POAG1 (%) (n = 249) | Controls (%) (n = 317) | POAG1 vs. Control |
POAG2 (%) (n = 204) | POAG2 vs. Control |
POAG Combined (%) (n = 455) | POAG Combined vs. Control |
|||
|---|---|---|---|---|---|---|---|---|---|---|
| P* (P†) | OR (95% CI) | P* (P†) | OR (95% CI) | P* (P†) | OR (95% CI) | |||||
| H1/H1 | 18.88 | 15.14 | NS | 1.30 (0.82–2.08) | 19.61 | NS | 1.37 (0.84–2.23) | 17.80 | NS | 1.21 (0.81–1.83) |
| H1/H2 | 20.88 | 12.93 | 0.01 (0.04) | 1.79 (1.11–2.87) | 18.14 | NS | 1.49 (0.89–2.49) | 19.56 | 0.01 (0.04) | 1.64 (1.08–2.51) |
| H1/H3 | 11.24 | 9.46 | NS | 1.21 (0.68–2.17) | 6.86 | NS | 0.70 (0.38–1.28) | 9.23 | NS | 0.97 (0.58–1.65) |
| H2/H2 | 8.43 | 3.15 | 0.006 (0.02) | 2.83 (1.24–6.85) | 4.41 | NS | 1.42 (0.50–3.95) | 5.93 | 0.052 (NS) | 1.94 (0.89–4.55) |
| Rest of diplotypes | 40.56 | 59.31 | — | — | 50.98 | — | 47.47 | — | ||
Individual diplotypes inferred with a probability >0.7 and with frequencies higher than 5% in at least one of the groups are shown. Only diplotypes with frequencies larger than 7% in at least 1 of the 2 groups were analyzed. NS, not significant.
Pearson's χ2 test of individual diplotypes grouping all others together.
Bonferroni corrected.