Table 3.

Results of Association Testing of HGF SNPs in Multiple Cohorts

Cohort	rs3735520				rs17501108/rs1014091*
	MAF		P	OR (95% CI)	MAF		P	OR (95% CI)
	Controls	Cases			Controls	Cases
Pooled+Rep1	0.41	0.51	0.002	1.50 (1.15–1.94)	0.14	0.07	0.0002	2.33 (1.17–3.69)
Rep2	0.43	0.45	0.664	1.08 (0.76–1.51)	0.17	0.10	0.006	1.93 (1.20–3.10)
US1	0.45	0.57	6.1 × 10−7	1.63 (1.35–1.98)	0.11	0.07	0.018	1.56 (1.07–2.24)
US2	0.46	0.47	0.655	1.05 (0.86–1.28)	0.11	0.10	0.658	1.08 (0.77–1.50)

The minor allele frequency in cases and controls are shown. OR (95% CI) is also shown, expressed with respect to the risk allele defined in the pooled samples.

^*As rs17501108 and rs1014091 are in very strong LD (r² = 0.95 in Australian samples), the results for rs17501108 are presented for Australian samples and rs1014091 for U.S. samples, due to different genotyping strategies in the two cohorts.