Table 1.
The passive membrane properties of GAD67+ GABAergic neurons in spinal lamina II
| Recorded with normal pipette solution | Recorded with SB202190 in pipette | |||||||
|---|---|---|---|---|---|---|---|---|
| Tonic firing | Initial bursting | P | Delayed firing | Single spike | Tonic firing | Initial bursting | P | |
| Cm (pF) | 42.1 ± 2.5 | 42.0 ± 5.4 | 0.98* | 37.3 ± 10.6 | 19.0 & 41.2 | 43.5 ± 3.0 (P = 0.77*) | 42.7 ± 2.2 (P = 0.58†) | 0.92* |
| Rin (MΩ) | 458.7 ± 47.4 | 350.8 ± 62.0 | 0.16† | 499.4 ± 58.2 | 337.9 & 218.7 | 449.0 ± 35.2 (P = 0.47†) | 380.2 ± 43.6 (P = 0.34†) | 0.32* |
| RMP (mV) | −50.7 ± 1.1 | −52.8 ± 2.4 | 0.35* | −61.3 ± 1.9 | −42.0 | −52.7 ± 1.4 (P = 0.26*) | −53.6 ± 2.6 (P = 0.85*) | 0.75* |
| CT (pA) | 39.7 ± 4.8 | 48.5 ± 6.5 | 0.14† | 76.7 ± 38.5 | 100.0 & 60.0 | 34.8 ± 3.1 (P = 0.66†) | 42.9 ± 5.2 (P = 0.57*) | 0.21† |
| N | 32 | 13 | 3 | 2 | 23 | 7 | ||
Values are mean ± SEM. P value in the column: tonic vs. initial bursting neurons recorded with the same pipette solution. P value in parentheses: recorded with vs. without SB202190 in pipette solution for the same type of neurons.
*
Student's t test
†
Wilcoxon rank-sum test.
Cm, membrane capacitance; Rin, input resistance; RMP, resting membrane potential; CT, current threshold for action potential.