Effect of Th2 environment on macrophage polarization. A. OVA sensitization and challenge alters the mRNA expression of macrophage activation markers. Data are fold-increase compared to macrophages from PBS-treated mice (N=3-4, bars represent mean±SEM). B. Effect of IL-4/IL-13 incubation on the eotaxin response to RV infection in macrophages from PBS-treated naïve mice. (N=3, bars represent mean±SEM.of fold increase in mRNA expression compared to control cells, mean±SEM, *P<0.05, one-way ANOVA).