Table 3.

A comparison of select age-adjusted cardiovascular risk factors in individuals with normotension and normoglycemia, prehypertension and prediabetes, and hypertension and diabetes

	Normotension-normoglycemia		Prehypertension-prediabetes		Hypertension-diabetes
	N	$\overline{x}\pm s/M({\text{Q}}_{\text{R}})$	N	$\overline{x}\pm s/M({\text{Q}}_{\text{R}})$	N	$\overline{x}\pm s/M({\text{Q}}_{\text{R}})$	P-valuea	P-valueb
BMI (kg/m2)
Men	645	22.5 ± 3.2	512	25.4 ± 3.5	96	26.6 ± 3.1	< 0.0001	0.0018
Women	1692	22.2 ± 3.9	384	24.6 ± 3.2	61	26.8 ± 3.7	< 0.0001	< 0.0001
WC (cm)
Men	628	79.0 ± 9.7	498	88.1 ± 9.3	97	92.2 ± 8.5	< 0.0001	< 0.0001
Women	1654	73.3 ± 8.3	376	82.0 ± 8.8	60	88.7 ± 9.8	< 0.0001	< 0.0001
SBP (mmHg)	2430	108.9 ± 7.2	897	126.3 ± 6.9	160	148.9 ± 15.6	< 0.0001	< 0.0001
DBP (mmHg)	2430	70.1 ± 6.0	897	80.4 ± 5.7	160	91.8 ± 10.1	< 0.0001	< 0.0001
GGT (U/L)	2339	15.4 (12.0-22.9)	897	28.6(18.0-48.9)	160	38.1(25.0-64.0)	< 0.0001	< 0.0001
UA (μmol/L)	2339	274.9 ± 74.6	897	333.4 ± 86.4	160	321.3 ± 78.3	< 0.0001	0.0984
GLU (mmol/L)	2340	5.0 ± 0.4	897	6.0 ± 0.3	160	9.1 ± 2.5	< 0.0001	< 0.0001
TG (mmol/L)	2340	0.97(0.73-1.35)	897	1.58(1.08-2.35)	160	2.22(1.52-3.25)	< 0.0001	< 0.0001
TC (mmol/L)	2340	4.4 ± 0.9	897	5.0 ± 1.1	160	5.3 ± 1.1	< 0.0001	0.0015
HDL-C (mmol/L)	2334	1.5 ± 0.3	895	1.4 ± 0.4	160	1.3 ± 0.3	< 0.0001	0.0026
LDL-C (mmol/L)	2340	2.3 ± 0.8	897	2.8 ± 0.9	160	3.1 ± 0.9	< 0.0001	0.0001

¹GGT and TG were reported as medians (interquartile range).

²Age-adjusted by analysis of covariance.

³Abbreviations: BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; GGT, γ- glutamyltransferase; UA, uric acid; GLU, glucose; TG, triglyceride; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol.

^a Normotension-normoglycemia vs. prehypertension-prediabetes

^b Prehypertension-prediabetes vs. hypertension-diabetes