Table 2.
Oral Administration of 1% and 2% Green Tea, Phytic Acid, and Inositol in Combination Reduced the Tumor Incidences, Total Number of Colon Tumors, and Average Tumor Size in Fisher 344 Male Rats
| |
|
|
% incidence |
Total number of colon tumors |
|
||
|---|---|---|---|---|---|---|---|
| Level, group | N1/N2 | % colon tumor incidence | Distal | Proximal | Distal | Proximal | Average tumor size (mm) |
| Control | 16/17 | 94a | 92 | 8 | 33 | 3 | 15.95±0.98a |
| 2% | |||||||
| GT+PA | 5/14 | 36c | 100 | 5 | 2.40±0.19bc | ||
| GT+I | 5/11 | 45b | 83 | 17 | 5 | 1 | 2.60±0.21bc |
| PA+I | 5/13 | 38c | 100 | 6 | 2.80±0.46bc | ||
| GT+PA+I | 3/13 | 23c | 100 | 3 | 1.30±0.06c | ||
| 1% | |||||||
| GT+PA | 6/14 | 43b | 100 | 10 | 6.30±0.86b | ||
| GT+I | 7/14 | 50b | 100 | 13 | 6.20±0.85b | ||
| PA+I | 5/11 | 46b | 100 | 8 | 10.00±0.88a | ||
| GT+PA+I | 5/11 | 46b | 100 | 7 | 4.10±0.62b | ||
Data are mean±SEM values (n=11–17).
abc
Means in a column not sharing the same letter differ, P<.05.
N1, number of rats having tumors; N2, number of rats at the end of the experiment.