Table 1.
Univariate and multivariate Cox regression analysis for progression free survival
Univariate analysis | Multivariate analysis | ||||||
---|---|---|---|---|---|---|---|
Factor | Patients (n = 248) | HR | 95% CI | p-val | HR | 95% CI | p-val |
TCF12 expression | |||||||
Neg/weak | 200 | 1 | Reference | 1 | Reference | ||
Strong | 48 | 2.03 | 1.03-4.01 | 0.04 | 2.24 | 1.17-4.73 | 0.02 |
Sex | |||||||
Female | 120 | 1 | Reference | ||||
Male | 128 | 1.82 | 0.95-3.51 | 0.07 | |||
Age at surgery | |||||||
< = 71 | 128 | 1 | Reference | ||||
>71 | 120 | 1.26 | 0.67-2.38 | 0.46 | |||
Tumour location | |||||||
Colon | 158 | 1 | Reference | ||||
Rectum | 90 | 1.11 | 0.57-2.08 | 0.80 | |||
T-stage | |||||||
pT3 | 226 | 1 | Reference | ||||
pT4 | 22 | 0.81 | 0.27-2.80 | 0.74 | |||
Tumor sizea | |||||||
<50 mm | 135 | 1 | Reference | ||||
>50 mm | 112 | 0.70 | 0.35-1.30 | 0.24 | |||
Histological typea | |||||||
Adenocarcinoma | 217 | 1 | Reference | ||||
Mucinous | 27 | 1.18 | 0.46-4.88 | 0.50 | |||
Number of nodesa | |||||||
< = 10 | 119 | 1 | Reference | 1 | Reference | ||
>10 | 119 | 2.01 | 1.00-4.04 | 0.05 | 2.10 | 1.00-4.03 | 0.05 |
HR = hazard ratio; 95% CI = 95% confidence interval.
aPatients with missing values were excluded from the analysis.