Table 2.

Heart rate on the day of the 30-min coronary occlusion

	Preocclusion	Occlusion, min		Reperfusion, min
		5	30	5	15	60
Group I	540±13	583±16	589±19	546±12	552±11	582±11
Group II	545±22	558±21	535±16	537±12	528±13	558±21
Group III	636±33*	675±25*	689±17*	679±11*	662±13*	670±15*
Group IV	548±18	562±20	543±23	570±22	540±25	532±18
Group V	549±13	556±20	539±20	533±20	529±20	529±20

Data are means ± SE (in beats/min). Measurements of heart rate were taken 5 min before the 30-min coronary occlusion (preocclusion), at 5 and 30 min into the 30-min occlusion, and at 5, 15, and 60 min after reperfusion. The experimental protocols for the 5 groups of mice are specified in METHODS. Note that the heart rate in group III (measured on day 2) was higher than that in groups I, II, IV, and V (measured on day 1), possibly reflecting the effect of surgical trauma 24 h earlier.

^*P < 0.05 vs. groups I, II, IV, and V.