TABLE 2.
Bone-Density Measures for Athletes With Amenorrhea, Athletes With Eumenorrhea, and Control Subjects
| Athletes With Amenorrhea (N = 21) | Athletes With Eumenorrhea (N = 18) | Control Subjects (N = 18) | P | |
|---|---|---|---|---|
| Lumbar BMD, mean ± SD, g/cm2 | 0.90 ± 0.11a | 0.99 ± 0.09 | 0.96 ± 0.09 | .01 |
| Lumbar BMD z score, mean ± SD | –0.76 ± 0.85a,b | –0.11 ± 0.87 | –0.10 ± 0.65 | .02 |
| Lumbar BMAD, mean ± SD, g/cm3 | 0.143 ± 0.015c | 0.153 ± 0.014 | 0.154 ± 0.017 | .045 |
| Lumbar BMAD z score, mean ± SD | –0.85 ± 0.80a,b | –0.06 ± 0.84 | –0.23 ± 0.96 | .02 |
| Lumbar BA for height z score, mean ± SD | –0.08 ± 0.88 | 0.08 ± 1.10 | 0.16 ± 0.97 | NS |
| Lumbar BMC for BA z score, mean ± SD | 0.16 ± 0.67a | 0.86 ± 0.84 | 0.54 ± 0.91 | .03 |
| Hip BMD, mean ± SD, g/cm2 | 0.89 ± 0.10a | 1.00 ± 0.10 | 0.96 ± 0.09 | .004 |
| Hip BMD z score, mean ± SD | –0.43 ± 0.75a | 0.28 ± 1.0 | –0.00 ± 0.80 | .04 |
| WB BMD, mean ± SD, g/cm2 | 0.98 ± 0.07a,c | 1.05 ± 0.08 | 1.03 ± 0.07 | .01 |
| WB BMD z score, mean ± SD | –0.58 ± 0.72a,c | 0.10 ± 1.00 | 0.04 ± 0.74 | .02 |
| WB BMC/height, mean ± SD, g/cm | 10.97 ± 1.35a,b | 12.33 ± 1.17 | 12.01 ± 1.17 | .003 |
| WB BMC/height z score, mean ± SD | –0.79 ± 0.54b | –0.41 ± 0.71 | –0.34 ± 0.50 | .04 |
| WB BA for height z score, mean ± SD | –0.06 ± 0.97a,c | 0.74 ± 0.94a | 0.60 ± 0.86 | .02 |
| WB BMC for BA z score, mean ± SD | –0.44 ± 1.14 | 0.34 ± 1.25 | –0.15 ± 1.13 | NS |
| PINP level, mean ± SD, μg/L | 102.7 ± 69.7b | 135.6 ± 73.7 | 205.6 ± 143.9 | .01 |
| N-telopeptide level, mean ± SD, nmol of bone collagen equivalent | 139.4 ± 119.8b | 173.2 ± 128.1 | 295.7 ± 293.1 | .05 |
NS indicates not significant.
a
P < .05, compared with athletes with eumenorrhea (Tukey-Kramer test to adjust for multiple comparisons).
b
P < .05, compared with control subjects.
c
P < .1, compared with control subjects.