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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Anal Chem. 2011 Feb 22;83(6):1890–1900. doi: 10.1021/ac102570t

Table 3.

Comparison of plate numbers at the Knox-Saleem Limita and what is achievable with 1.8 μm particlesb for a dead time of 5 s.

Condition KS Limit (N) dp*(μm)c 1.8 μm Limit (N) % Not Gainedd % Over 25/400e
25/400f 8990 1.2 7920
25/1000 14200 0.95 10200 28 29
120/400 16200 1.8 16100 1 103
120/1000 25630 1.5 25000 2 216
a

Calculated using eq 9, using the values specified for fully porous materials specified in Figure 2A.

b

Calculated as described in Figure 2.

c

Calculated using eq 4.

d

Calculated as the fraction of the KS limiting plate count (with a particle size of dp) that is not realized because of the 1.8 μm particle size limit.

e

Calculated as the improvement in the number of plates achieved relative to the performance obtained with 1.8 μm particles at 25 °C and 400 bar by increasing the pressure, temperature, or both.

f

Temperature (°C)/pressure (bar) combinations.